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Fri., June 8
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Congress Program - Friday, June 8

 
 08:30 - 10:00
Plenary 5
Regency Ballroom
  Chair: David McLean  
08:30 – 09:00
Mechanisms of Action of PDT – Cellular Mechanisms
David Kessel
09:00 – 09:30 Molecular Mechanisms Moving to Clinical Treatments Charles Gomer
09:30 – 10:00 Cardiovascular PDT Jean McEwan
10:00 – 10:30 Refreshment Break/Exhibits/Posters Regency East
10:30 – 12:00 Plenary 6 Regency Ballroom
  Chair: David McLean  
10:30 – 11:00 PDT in Urology Ronald Moore
11:00 – 11:30 Clinical Applications of PDT in Biliary and Pancreatic Diseases Stephen Bown
11:30 – 12:00 Head and Neck Cancer Merrill Biel
12:00 – 13:30 Lunch Break/Exhibits/Posters (lunch on own)
12:00 – 13:15 Visudyne™ Session (closed workshop) Grouse
  Visudyne™ Therapy for the Treatment of Wet Age-Related Macular Degeneration This session will be of interest to general ophthalmologists and those wishing to become familiarized with Visudyne™ therapy for the treatment of wet age-related macular degeneration. Several clinical examples will be reviewed, including diagnosis by fluorescein angiogram and narration of a Visudyne™ treatment. Michael J. Potter
13:30 – 15:00 Concurrent Symposia
Plaza East Dermatology (2 of 2)
Chairs: Colin A. Morton & Allan Oseroff
13:30 – 13:45 Indications for ALA-PDT in Cutaneous Malignancy Colin A. Morton
13:45 – 14:00 Skin PDT: Outcomes, Treatment, Parameters and Metrics Allan Oseroff
14:00 – 14:10 Photodynamic Therapy of Non-Melanoma Skin Cancers with Verteporfin and Red Light Tumor Response and Cosmetic Outcome Lori Hobbs
14:10 – 14:20 Topical ALA-Mediated Photodynamic Therapy of Superficial Basal Cell Carcinoma Using Two Light Fractions With a Two Hour Interval Willem M. Star
14:20 – 14:30 Kinetics of ALA-Induced Fluorescence of Human Skin Tumors In Vivo Christoph Abels
14:30 – 14:40 Long-Time Follow-up after ALA-PDT of Superficial Basal Cell Carcinoma Sigrid Karrer
14:40 – 14:50 Late Recurrence of Superficial Basal Cell Carcinoma Following ALA-PDT Joyce A. Leman
14:50 – 15:00 Photofrin Photodynamic Therapy for Nevoid Basal Cell Carcinoma Syndrome Sherry Shieh
15:00 – 15:10 Photodynamic Therapy for Chest Wall Progression from Breast Cancer is an Underutilized Treatment Modality Thomas S. Mang
Plaza Centre Infectious Diseases / Topical PDT (1 of 2)
Chairs: Tayyaba Hasan & Jun-Heng Li
13:30 – 13:42 Photodynamic Therapy for Wound Infections Michael R. Hamblin
13:42 – 13:54 Photodynamic Therapy of Oral Plaque Biofilms Formed In Vivo Simon R. Wood
13:54 – 14:08 Photodynamic-Ultrasonic Therapy of Infected Wound Vladimir P. Zharov
14:08 – 14:20 Oncological Applications of Photodynamic Therapy and Selective Laser Hyperthermia Mark L. Gelfond
14:20 – 14:32 Photodynamic Therapy and Topical Application of the New Photosensitizer MV6401 Stephanie F. Greene
14:32 – 14:44 ALA Penetration in Cutaneous Tumors: Measurement by Protoporpyrin IX Fluorescence and Correlation with Peripheral Benzodiazepine Receptor Expression Janet Morgan
14:44 – 14:56 Photodynamic Therapy for MRSA Nobuyuki Sakaniwa
14:56-15:10 Hypothetic Mechanism of ALA-PDT Induced Pain Bernd Algermissen
Balmoral Room Optical Diagnosis (2 of 2)
Chairs: Reinhold Baumgartner & Stefan Andersson-Engels 		 
13:30 – 13:50 5-ALA Assisted Imaging: News and Views Reinhold Baumgartner
13:50 – 14:00 Endoscopic Detection of Dysplasia and Early Cancer in Barrett’s Esophagus after Sensitization with 5-Aminolevulinic Acid Thomas Stepinac
14:00 – 14:10 Barrett’s Esophagus: High Detection Rate for Dysplasia and Early Adenocarcinoma by Combined Screening with 4-Quadrant Biopsies and Photodynamic Detection Gian O. Dorta
14:10 – 14:20 The Use of An Optical Biopsy System in Barrett’s Esophagus Kenneth K. Wang
14:20 – 14:30 Quantitative Fluorescence Imaging Annette McWilliams
14:30 – 14:40 Spectroscopic Diagnosis of Bladder Tumours Using Fluorescence Excitation-Emission Matrix Wei Zheng
14:40 – 14:50 Detection of Superficial Extension of Central Type Lung Cancer by Photodynamic Diagnosis Assisted with Fluorescent Endoscopy Takaaki Tsuchida
Plaza West Photosensitizers (3 of 3)
Chairs: Clifford Leznoff & Kevin Smith
13:30 – 13:39 Photodynamic Therapy (PDT) of a Gastric Cancer Cell Line Using Indocyanine Green (ICG) and a Low Power Laser Diode Christopher Russell
13:39 – 13:48 Comparative Spectroscopic Studies of Photosensitizer – Model Membrane Interactions Sarah Gerhardt
13:48 – 13:57 Uptake, and Localization of MTHPC and its 14C-Labeled Form in Normal and Tumoral Tissues of the Hamster Squamous Cell Carcinoma Model: A Comparative Study Snezana Andrejevic-Blant
13:57 – 14:06 Clinical Evaluation of a Promising New Chlorin E6 Derivative – Photochlorin 1 E. Ph. Stranadko
14:06 – 14:15 Photodynamic Inactivation of a Human Glioblastoma Cell Line Using 5-Aminolevulinic Acid-Induced Protoporphyrin IX – Modulation by Iron and Differentiating Agents Wolfgang Strauss
14:15 – 14:24 Evaluation of the Potential of Pyropheophoride-a Methyl Ester (MPPa) as a New Photosensitizer: A Comparison of its Photodynamic Efficacy and Yield of Oxygen Singlet with mTHPC X. Sun
14:24 – 14:33 Photodynamic Therapy on Normal Rat Colon Using Tookad (WST09), a Bacteriochlorophyll Derivative Josephine Woodhams
14:33 – 14:42 Symmetrical Phenothiazine Dyes as Potential Therapeutic Agents for Use in Photodynamic Therapy Andrea L. Bell
14:42 – 14:51 Tookad – A Novel Palladium-Bacteriochlorophyll Sensitizer for Photodynamic Therapy: Synthesis and Characterization Avigdor Scherz

14:51 – 15:00

Photodynamic Therapy (PDT) of Rat C6 Glioma Xenografts With Pd-Bacteriopheophorbide (Tookad) Leads to Decreased Metastases and Increased Animal Cure Compared to Surgery Smadar Schreiber
15:00 – 15:09 The Photochemical and Photophysical Mechanism Intiated by Excited PD-Bacteriochloropyll Derivative Vakrat Yahel
Stanley Room
34th Floor 		Urology / Gynecology (2 of 2)
Chair: Dieter Jocham
13:30 – 13:50 Long Term Results of PDT of Bladder Tumors Dieter Jocham
13:50 – 14:02 Simultaneous Auto- and Xenofluorescence in the Diagnosis of Cervical Intraepithelial Neoplasia Peter Hillemans
14:02 – 14:14 Application and Perspective of PDT and Chemotherapy to Stage Ib1 Cervical Cancer Tetsuya Muroya
14:14 – 14:26 Enhanced Photodynamic Ablation of the Rabbit Endometrium Using 5-Aminolaelvulinic Acid and the Iron-Chelating Agent CP94 Dilip Visvanathan
14:26 – 14:38 Autofluorescence Analysis of Bladder Cancer Using Laser Confocal Microscopy and Spectroscopy Malini Olivo
14:38 – 14:50 Macro-Microscopic Fluorescence Analysis of Bladder Cancer Using ALA Induced Fluorescence Cystoscopy and Laser Confocal Microscopy Malini Olivo
14:50 – 15:00 Photodetection of Ovarian Cancer with h-ALA Attila Major
15:00 – 15:30 Afternoon Break Plaza
15:30 – 17:00 Concurrent Symposia
Plaza Centre Regulatory Issues & Outcomes Research in PDT
Chairs: Michael Unger & Eric Edell
15:30 – 15:45 Evaluating Clinical Outcomes of Palliative PDT Teresa Goodell
15:45 – 16:00 Quality of Life as an Outcome of PDT for Barrett’s Esophagus Kathy B. Wright
16:00 – 16:15 Regulatory Issues Facing PDT Investigations John Hill
16:15 – 16:30 Selective Porphyrin Synthesis in Chemically Induced Skin Tumours: Implications in Cutaneous Photosensitisation Alcira Batlle
16:30 – 16:40 Our Experience in PDT with Photosensitzers of Different Groups Evgueni Ph. Stranadko
Plaza East Topical PDT (2 of 2)
Chairs: Roy Pottier & Qian Peng 		 
15:30 – 15:50 Topical Photodynamic Therapy in Dermatology: The How’s, The Why’s and the Why Not’s Alexis Sidoroff
15:50 – 16:10 PDT of BCC & AK with Metvix Trond Warloe
16:10 – 16:20 Photodynamic Diagnosis, Therapy and Real-Time Treatment Control Arie Orenstein
16:20 – 16:30 Superficial Temperature and Perfusion Measurements in Connection with PDT of Basal Cell Carcinomas Sara Palsson
16:30 – 16:40 Optimising Illumination Protocols for ALA-PDT Dominic J. Robinson
16:40 – 16:50 Effect of Photodynamic Treatment With Superficial Application of 5-Aminolaevulinic Acid (ALA) on Implantable Breast Cancer in Mice Miroslaw Stec
16:50 – 17:00 A Study on the Penetration of 5-Aminolaevulinic Acid and its Methyl and Hexyl Esters Through Normal and UVB Treated Hairless Mouse Skin David I. Vernon
Stanley Room
34th Floor 		Immunomodulation
Chairs: Sandra Gollnick & Mladen Korbelik		  
15:30 – 15:50 Generation of Anti-Tumor Vaccines Using PDT Sandra Gollnick
15:50 – 16:10 Engagement of PDT-Induced Host Immune Defence Mechanisms in the Eradication of Cancerous Lesions Mladen Korbelik
16:10 – 16:20 Increased Cytoxotic Effects of Photodynamic Therapy in IL-6 Gene Transfected Cells via Enhanced Apoptosis Shuji Ichinose
16:20 – 16:30 Topical ALA-PDT Modifies Cytokine Levels in Serum of Patients with Skin Tumours Mariusz Adamek
16:30 – 16:40 Influence of Host Immunity in Photodynamic Therapy Gianfranco Canti
16:40 – 16:50 Effect of PDT With QLT0074 on Cytokine Release From Human Endothelial Cells Anthea Tench Stammers
16:50 – 17:00 Potentiation of Therapeutic Efficacy of PDT by In Vivo Administration of Cyclophosphamide and Limphokine Activated Killer Cells on Rat Ascites Tumor Cells Dima F. Vasile
17:00 – 17:10 Pre-Clinical Trials of h-ALA for PDT of Rheumatoid Arthritis Norbert Lange
Balmoral Room Mechanisms of Action (3 of 3)
Chairs: Barbara Henderson & Nancy Oleinick 		 
15:30 – 15:40 Spectral Characteristics, Photocytotoxicity, Intracellular Localization of a New Chlorophyll-Derived Photosensitizer of Pyropheophoride-a Methyl Ester (MPPa) in Human Lung Carcinoma Cancer Cell and its Induced Apoptosis Albert W.N. Leung
15:40 – 15:50 Combination Therapy of a Cultivated Leukemia Cell with Photoradiation and Sonolysis Norio Miyoshi
15:50 – 16:00 Carrier Protein of Water-Soluble Tumor Localizing Porphyrin-Atn-2, ATX-S10 (Na) Susumu Nakajima
16:00 – 16:10 Oxygen Dynamics During PDT: Comparison of In Vivo and In Vitro Effects for Vascular Versus Cellular Targeting Sensitizers Brian W. Pogue
16:10 – 16:20 Involvement of the Tumour Microcirculation in Aminolaevulinic Acid (ALA) Based Photodynamic Therapy (PDT) In Vivo F. Ruth Potter
16:20 – 16:30 Influence of Oxygen Level on Aminulevulinic Acid (ALA) Mediated Protoporphyrin IX (PPIX) Accumulation and Photodynamic Damage Joachim Rauch
16:30 – 16:40 Confocal Laser Scanning Microscopy to Investigate Dose Dependent Cell Death Mechanisms During AlPCS4 - PDT in Adherent Cells Angelika Ruck
16:40 – 16:50 Subcellular Time-Resolved Microspectrofluorometry of ALA-PPIX and mTHPC Using Short Pulsed Diode Lasers Angelika Ruck
16:50 – 17:00 Influence of Steroid Hormones and Steroid Hormone Antagonists On Photodynamic Inactivation In Vitro Reinhard Sailer
17:00 – 17:10 Mechanism Underlying the Potentiating Effect of a Transient Thrombocytopenia on Photofrin-Based Photodynamic Therapy Wim Sluiter
17:10 – 17:20 Endogenous Protoporphyrin IX (PPIX) Production in Rat Pancreatoma Cells from d-Aminolaevulinic Acid (ALA) and N-Pentyl ALA Ester Caroline J. Whitaker
17:20 – 17:30 Real-Time Image Analysis of PDT Cell-Death In Vitro With a Cooled Color CCD Camera Under a Confocal Laser Video-Microscope Takato O. Yoshida
Plaza West Dosimetry (2 of 2)
Chair: Michael Patterson
15:30 – 15:50 Progress in PDT Dosimetry Michael Patterson
15:50 – 16:00 Detection of PDT-Generated Singlet Oxygen in In Vitro and In Vivo by Near-Infrared Luminescence Brian C. Wilson
16:00 – 16:10 Monitoring Photoproduct Formation and Photobleaching by Fluorescence Spectroscopy Improves PDT Dosimetry Haishan Zeng
16:10 – 16:20 Long-Term Stability of Silicon Photodiode Calibration for In Vivo Dosimetry in Photodynamic Therapy Timothy C. Zhu
16:20 – 16:30 The Effect of PDT on In Vivo Oxygen Saturation and Microvascular Circulation Josephine Woodhams
16:30 – 16:40 Observation of the Binding State Between Human Serum Albumin and Mono-L-Aspartyl Chlorin E6 Using the Surface Plasmon Resonance Phenomenon Taichiro Ishizumi
16:40 – 16:50 Measuring Blood-Flow Changes of Tumor Implanted in Mice by Noninvasive Optical Multichannel Oxygen Monitor Junichi Nitadori
19:00 Banquet Regency Ballroom

 
IPA 8th World Congress of Photodynamic Medicine  
www.dermweb.org/pdt2001  
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Updated: May 27, 2001